The 46th edition of the leading clinical reference on treatment of infectious diseases and anti-infective drug information. Popular with physicians, pharmacists, physician assistants, nurse practitioners, and other clinicians, the Sanford Guide to Antimicrobial Therapy provides information that is convenient, concise, and reliable. Coverage includes: - Clinical syndromes pathogens bacterial fungal mycobacterial parasitic viral - Anti-infective agents dosing: .pediatric adjustments .renal adjustments adverse affects activity pharmacology interactions - Preventative therapy Areas of significant change in this 46th edition include: - Initial Approach to Antimicrobial Therapy: Significant updates to genital tract infections based on new CDC STD Guidelines, empiric therapy for pneumonia, and updated regimens and references. - Spectra of Activity: Completely reworked table with more descriptive classification system, printed in color for improved ease of use. - Drug Desensitization: Desensitization methods for additional drugs have been added. - Antimicrobial Use During Lactation: New table on the safety of antimicrobials in lactating mothers. - HCV: New direct-acting agents and combination agents, along with updated HCV treatment regimens. - Pediatric Dosing: New table summarizing dosing of antimicrobials in children age 28 days or older. - Renal Impairment Adjustments: Table has been thoroughly reworked to improve ease of use. - New Drugs: ceftazidime-avibactam, ceftolozane-tazobactam, isavuconazole.