From award-winning, New York Times bestselling author and neuroscientist Lisa Genova comes a heartbreaking very human novel (Matthew Thomas, author of We Are Not Ourselves) that does for Huntingtons disease what her debut novel Still Alice did for Alzheimers. Joe OBrien is a forty-three-year-old police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, proud father of four children in their twenties, and respected officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to the stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his familys lives forever: Huntingtons disease. Huntingtons is a lethal neurodegenerative disease with no treatment and no cure, and each of Joes four children has a 50 percent chance of inheriting their fathers disease. While watching her potential future in her fathers escalating symptoms, twenty-one-year-old daughter Katie struggles with the questions this test imposes on her young adult life. As Joes symptoms worsen and hes eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while Katie and her siblings must find the courage to either live a life at risk or learn their fate.